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Transforming orthopaedics and regenerative medicine through pioneering use of nanoclay gels stemming from world-class stem cell research

Transforming orthopaedics and regenerative medicine through pioneering use of nanoclay gels stemming from world-class stem cell research

Investment Opportunity in Regenerative Medicine

Renovos is an exciting opportunity for bioscience investors who share our vision of innovation in the regenerative medicine space supporting active living across the lifespan.

Our motivation is to unlock the full potential of regenerative medicine with our innovative Renovite® nanoclay gel technology platform, and help clinicians deliver safer and more efficacious treatments for tissue repair.

 

Growing market and need

$ 0 bn
spinal fusion and foot and ankle markets
> 0 m
spinal fusion procedures worldwide each year
>$ 0 bn
orthobiologics market, growing rapidly

Renovos is focusing on the orthobiologics and regenerative medicine markets, whose growth is driven by both a global ageing population and more active younger demographics, damaging their tissues through sports. The RENOVITE® platform will deliver products that are easier to use and more effective, and most importantly safer.

The anticipated commercial and health economic proposition for the first product, RENOVITE® BMP-2 gel (addressing c. $1bn market), as well as following biologics products based on the RENOVITE® platform, is clear:

the safe and rapid application of the biologic will reduce the incidence of failed procedures and associated revisions, allowing for an attractive price point for the product while taking significant costs out of the healthcare system

as a product injectable via a narrow gauge needle, it can further expand the addressable market by facilitating application of biologics in minimally invasive procedures with high precision and saving time in the theatre

the decreased risk of adverse events and ectopic bone formation should allow for access to biologics for higher risk patients as well as in other procedures, which further extends the economic impact to previously unserved patient pools.

Broad Platform Technology

bone and cartilage
Bone / Cartilage
tooth
Dental
skin diagram
Skin

Broad Platform Technology

knee cartilage and spine

Bone / Cartilage

tooth

Tooth

skin diagram

Skin

Renovos is pioneering the use of synthetic nanoclay gels for medical use. The RENOVITE® nanoclay gel platform can be used to deliver and retain biologics, and promote tissue regeneration in multiple applications, making step-change improvements in a wide range of current procedures. Our proprietary formulations:

are ready to use and easy to handle

form a biodegradable gel after injection which templates new tissue formation

can deliver biologics with efficacy at ultra-low doses

retain the biologics and release only to regenerative cells growing into the nanoclay, for increased safety and efficacy.

Novel breakthrough technology but with a low technical risk and easy scale-up

Various nanoclays are already used as components in some drugs and cosmetics and carry low developmental risk. All of Renovos’ work is underpinned by decades of rigorous research and validation by the same core team. Consequently, this has built up the skills and know-how of the team, facilitating technical success and rapid product development. Renovos’ core skills and IP are in formulation and development, and all the processes developed to date can be expanded and scaled without major technical challenges.