RENOVITE®, a synthetic nanoclay for precision therapeutics delivery
RENOVITE®, a synthetic nanoclay gel scaffold for effective localised therapeutics delivery
Renovos is pioneering synthetic nanoclays for medical applications
For decades, clays have been used in tablets to control drug release through their molecule binding properties. For instance, these binding properties ensure that molecules stay localised. Renovos has developed an innovative solution to molecule diffusion based on synthetic nanoclay, RENOVITE®. RENOVITE® provides a localised environment conductive to cell infiltration, whilst retaining bioactive molecules, until it is gradually replaced with newly regenerated tissue, acting as a precise template.
RENOVITE® BMP-2 – our nanoclay based orthobiologic
Clinical use of the BMP-2 protein for spine fusion has severe safety and handling limitations. To overcome these, we have developed RENOVITE® BMP-2, an injectable carrier based on synthetic nanoclay that binds and delivers BMP-2 to allow precise templating of new bone formation, and therefore safer and more efficient bone fusion.
RENOVITE® BMP-2 offers:
High-precision handling
RENOVITE® BMP-2 is injectable and can pass through a 23G needle
Retention at target site
RENOVITE BMP-2 remains where injected and retains BMP-2 at site whilst new bone forms
Improved bone fusion quality
RENOVITE BMP-2 leads to higher quality of regenerated bone, avoiding the common “eggshell effect”
Key advantages of RENOVITE® nanoclay technology:
Improved safety
reduced non-specific effects
Easy to use
injectable and suitable for minimally-invasive procedures
Improved efficacy
sustained localised retention, leading to higher bioavailability
Customisable
able to deliver a broad variety of molecules
Reduced costs
reduced biologic doses and reduced need for revision procedures
Biocompatible and resorbable
gradually replaced with newly regenerated tissue